Written by Merel Dagher (PEACE Advisor)
Select all that apply regarding the correct definition of the isoelectric point of peptides (More than one may be correct):
a. At the pI, the net charge of the molecule is zero
b. At pI, the the carboxy group is deprotonated and the amino group is protonated.
c. At pI, proteins are less soluble in water
d. The addition of side chains can change the protein’s pI.
a. At the pI, the net charge of the molecule is zero
b. At pI, the the carboxy group is deprotonated and the amino group is protonated.
c. At pI, proteins are less soluble in water
d. The addition of side chains can change the protein’s pI.
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All of the choices are correct.